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Jessica Winter

  • Professor, Chemical & Biomolecular Eng
  • Professor, Biomedical Engineering
  • 453 CBEC
    151 W. Woodruff Ave.
    Columbus, OH 43210
  • 614-247-7668

About

Education

  • Ph.D., University of Texas at Austin, 2004
  • M.S., University of Texas at Austin, 2001 
  • B.S., Northwestern University, 1997 

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Professor Winter is an established leader in nanobiotechnology with applications to cancer. Her primary research interest is the exploration of the relationship between nanoparticles and biological elements.

She developed the Quantum Dot imaging innovation, a high-caliber magnetic fluorescent nanoparticle surpassing previous attempts in practical qualities which shines in different colors to tag molecules in biomedical tests such as cancer detection. The refined particle could help researchers to significantly reduce costs, increase the efficiency of their research, better identify and understand disease progression, and improve patient outcomes. With this technology she founded a start-up company, Core Quantum Technologies, LLC, which is working towards selling the substantially-improved quantum dot and magnetic dot products to the research biotechnology market.  

As a member of the QSTORM team, Winter participates in a multi-university, multi-disciplinary research venture funded by the National Science Foundation (NSF) to take a high-risk, high-reward approach to improving super-resolution biological imaging. The QSTORM team is developing a new microscope capable of peering through layers of tissue to witness fundamental activities of life occurring at the molecular scale. This new imaging tool may help lead the way to significant breakthroughs in medicine, agriculture and bioengineering.

She holds two patents.

 

 

Honors

  • May, 2016

    Diversity Award.

  • April, 2016

    American Institute of Medical and Biological Engineers Fellow.

  • April, 2016

    Engineering Rising Star.

  • January, 2016

    Cancer Today, Cover Story.

  • January, 2015

    40 Under 40.

  • February, 2014

    20 People to Know in Technology.

  • January, 2014

    Women Chemists Rising Star Award.

  • January, 2014

    Heaven-and-Earth Distinguished Lecture.

  • January, 2014

    AAAS Fellow.

  • October, 2013

    Senior Member Status.

  • May, 2013

    COE Harrison Award.

  • May, 2013

    Archer Award.

  • May, 2013

    Top 25 STEM Professors in Ohio.

  • February, 2013

    TechColumbus Inventor of the Year.

  • January, 2012-
    January, 2013

    Semi-finalist Columbus Tech Innovation Awards, Woman in Technology.

  • January, 2010-
    January, 2013

    Semi-Finalist Innovator of the Year.

  • October, 2012

    Ohio State University Early Innovator Award.

  • January, 2011

    Distinguished Undergraduate Research Mentor.

  • January, 2010

    David C. McCarthy Engineering Teaching Award.

  • January, 2010

    COE Lumley Research Award.

  • January, 2009

    Senior Member Status.

  • January, 2008

    Outstanding Undergraduate Achievement Mentor.

  • January, 2008

    ACS Progress/Dreyfus Lectureship Award.

  • January, 2007

    OSU Office of Technology Enhanced Learning and Research (TELR) Professional Development Grant (OSU).

  • January, 2001-
    January, 2004

    NSF Graduate Research Fellowship.

  • January, 2003

    Graduate Student Award.

  • January, 2003

    MRS Gold Graduate Student Award.

  • January, 1999-
    January, 2001

    IGERT Graduate Research Fellowship.

  • January, 2001

    Rom Rhome Endowment for Professional Development in Material Science Travel Award.

  • January, 2000

    IGERT Travel Award.

Presentations

  • "Degradable Polymeric Hydrogels for Neurotrophin Elution from Implanted Prosthetic Devices." 2006, Presented at AIChE National Meeting,
  • "Brain Mimetic Coatings to Enhance Neural Prosthesis Biocompatibility." 2009, Presented at Medical Materials Conference,
  • "Combining Fluorescent Imaging and Magnetic Force in Single Molecule Studies." 2009, Presented at AIChE National Meeting,
  • "Fluorescent Nanocomposites." 2010, Presented at Department Seminar: OSU,
  • "Investigating glioblastoma behavior in 3D culture using hydrogel biomaterials (poster)." 2010, Presented at BMES Annual Meeting,
  • "Neurotrophin-Releasing Hydrogel-Electrospun Fiber Mat Composite Coatings for Neural Prostheses." 2010, Presented at AIChE National Meeting,
  • "Directed Interfacing of Neurons and Semiconductors Using Quantum Dots Functionalized with Biological Recognition Molecules." 2000, Presented at AIChE National Meeting,
  • "Biomolecule-Directed Interfacing between Semiconductor Quantum Dots and Nerve Cells." 2001, Presented at Houston Society for Engineering in Medicine and Biology Annual Conference,
  • "Tissue Engineering the Brain-Machine Interface." 2007, Presented at Department Seminar: OSU,
  • "Adhesion Molecules Promote Chronic Neural Interfaces Following Neurotrophin Withdrawal." 2009, Presented at IEEE EMBS Conference (31st Annual),
  • "Simultaneous Magnetic Manipulation and Fluorescent Tracking of Single Sub-100nm Nanoparticles." 2009, Presented at BMES Annual Meeting,
  • "Contrasting effects of 2D vs. 3D hydrogel microenvironments on the behavior of glioblastoma multiformes (poster)." 2010, Presented at Society for Biomaterials (SFB) Annual Meeting,
  • "Integrating nanotechnology with neural prostheses." 2010, Presented at Monte Verita Conference: Frontiers in Neuroengineering,
  • "Electrospun Fiber-Glia White Matter Mimetics." 2011, Presented at Society for Biomaterials Annual Meeting,
  • "Quantum Dot – Neuron Interactions." 2003, Presented at BMES Annual Meeting,
  • "Neurotrophin Releasing Hydrogels for Improved Electrode-Cell Electrical Contacts in the Retinal Implant." 2005, Presented at MRS Fall Meeting,
  • "Using Functionalized Gold Nanoparticles to Promote Cell Adhesion in Agarose." 2008, Presented at AIChE Regional Meeting,
  • "Poly (ethylene glycol)-Poly (caprolactone) Hydrogels for Drug Delivery." 2008, Presented at ACS Regional Conference,
  • "Non-Synthetic Polymer Biomodification Using Gold Nanoparticles." 2008, Presented at AIChE National Meeting,
  • "A Novel, Low Cost Method for Investigating the Effect of Nanotopography On Biomaterials." 2009, Presented at AIChE National Meeting,
  • "Hyaluronic Acid-Collagen Blend Hydrogels: 3D ECM Mimics to Investigate Tumor Cell Migration." 2010, Presented at AIChE National Meeting,
  • "Semiconductor-Neural Interfaces." 2002, Presented at IEEE EMBS-BMES Joint Conference,
  • "Biocompatible Quantum Dots for Electrical Stimulation of Neural Cells." 2005, Presented at SPIE Photonics West,
  • "Neurotrophin-Eluting Hydrogel Coatings for Stimulating Electrical Prostheses." 2006, Presented at (MS&T) Materials Science & Technology 2006,
  • "Tissue Engineering Applied to Neural Prostheses." 2007, Presented at Department Seminar: OSU,
  • "Bifunctional Quantum Dot-Iron Oxide Nanoparticle Composites." 2007, Presented at AIChE National Meeting,
  • "Polymer hydrogel thin film coatings for acute drug delivery from neural prostheses." 2008, Presented at ACS Fall Meeting,
  • "Neural Biomaterials for Imaging, Drug Delivery, and Biomimetics." 2009, Presented at Department Seminar: OSU,
  • "Using Podcasts in the Classroom." 2010, Presented at OSU TELR,
  • "Hydrogel-electrospun fiber mat composites as controlled delivery systems for nerve generation." 2010, Presented at Society for Biomaterials (SFB) Annual Meeting,
  • "Innovative, Inexpensive Surfaces to Investigate the Effect of Nanotopography on Cells." 2010, Presented at ACS Regional Conference,
  • "Brain Mimetic Materials." 2010, Presented at Glioblastoma Multiforme Study Group,
  • "ain Mimetic Hydrogels for investigating migration of glioblastoma multiformes in 3D." 2011, Presented at Society for Biomaterials Annual Meeting,
  • "Nanoparticle-Polymer Composistes for Neural Interfaces." 2008, Presented at Department Seminar: Rice University,
  • "Development of a Neural Tissue Mimetic via Encapsulation of PC-12 Cells in Agarose Gel." 2008, Presented at AIChE Regional Meeting,
  • "Combined Effect of Brain-Derived Neurotrophic Factor and ECM-Coated Substrates on Neurite Extension and Persistence from Retinal Explants." 2006, Presented at AIChE National Meeting,
  • "Multi-Color Nanoparticles for Single Particle Tracking." 2010, Presented at AIChE National Meeting,
  • "Biodegradable Polymeric Hydrogels for Improved Neuroprosthetic-Tissue Interfaces." 2006, Presented at Department Seminar: Andrews University,
  • "Optimization of Quantum Dot – Nerve Cell Interfaces." 2003, Presented at MRS Fall Meeting,
  • "Surface Modification Of Neural Prostheses For Improved Neurite Extension And Persistence." 2006, Presented at BMES Annual Meeting,
  • "Drug Delivery From Neural Prostheses Using Polymer Composites." 2007, Presented at AIChE National Meeting,
  • "Thin Film Polymer Composites for Tissue Engineering of Neural Prostheses." 2007, Presented at MRS Fall Meeting,
  • "Podcasting in the Introductory Mass and Energy Balance Course." 2007, Presented at AIChE Annual Meeting,
  • "Mechanical Manipulation of Specific Intracellular Structures Rendered by Targeted Nanoprobes." 2007, Presented at MRS Fall Meeting,
  • "Nanomaterials for Neural Engineering." 2007, Presented at Department Seminar: OSU,
  • "Engineering magnetic-fluorescent nanocomposites for clinical imaging, cell separation and subcellular manipulation." 2008, Presented at ACS Fall Meeting,
  • "Fluorescent-Magnetic Nanoparticle Composites for Imaging, Cell Separation, and Cell Manipulation." 2008, Presented at Department Seminar: Cornell University,
  • "Drug Releasing Hydrogel-Electrospun Fiber Mat Composites to Enhance Nerve Regeneration (Poster)." 2009, Presented at BMES Annual Meeting,
  • "Drug Releasing Hydrogel-Electrospun Fiber Mats Composites to Enhance Nerve Regeneration." 2009, Presented at BMES Annual Meeting,
  • "PLGA-Encapsulated Graphitic Carbon and Iron Oxide Nanoparticles for Simultaneous Fluorescence and MR Imaging." 2009, Presented at AIChE National Meeting,
  • "Multimodal Nanocomposites for In vitro and In vivo Imaging." 2010, Presented at Department of Chemical and Biomolecular Engineering, Ohio University,
  • "Drug Delivery Systems to Promote Electrode-Host Integration in Retinal Prostheses (Poster)." 2007, Presented at (ARVO) Association for Research in Vision and Ophthalmology,
  • "Neural Prostheses at Different Length Scales." 2007, Presented at Department Seminar: University of Maryland, Baltimore County,
  • "Nanoparticle Materials for the Neural Interface." 2007, Presented at Gordon Research Conference: Organic Thin Films,
  • "Using Functionalized Gold Nanoparticles to Promote Cell Adhesion in Agarose." 2008, Presented at AIChE Columbus Chapter Local Meeting,
  • "Polymer Supported Gold Nanoparticle Biosensors." 2008, Presented at ACS Regional Conference,
  • "Engineering Magnetic-fluorescent Nanocomposites for Clinical Imaging, Cell Separation and Subcellular Manipulation." 2008, Presented at International Conference on Bioengineering and Nanotechnology,
  • "Polylysine modified PEG-based hydrogel materials for enhanced neural tissue-electrode contact (Poster)." 2009, Presented at BMES Annual Meeting,
  • "Nanotechnology for Cancer Detection." 2011, Presented at Seminar at Texas A&M University,
  • "Synthesis and Optimization of Polymer Micelles Formed Via Electroscopy-Enabled Interfacial Instability." 2013, Presented at AIChE Annual Meeting,
  • "Tuning mechanics and surface chemistry independently in biomaterial scaffolds to modulate cell behavior." 2013, Presented at ACS National Meeting,
  • "Magnetic quantum dot enabled technologies for nanoscale manipulation." 2013, Presented at ACS National Meeting,
  • "Using Nanoparticles to Diagnose Disease." 2013, Presented at Coalition for National Science Funding,
  • "Neural Biomimetic Materials for Examining Cell Migration in Disease Progression." 2013, Presented at AIChE Annual Meeting,
  • "Magnetic Quantum Dots for Quantitative Cell and Molecular Separations." 2014, Presented at Colloidal Semiconductor Nanoparticles Gordon Research Conference,
  • "Toward Nanomachines: Bio-Inspired Assembly, Transport and Manipulation at the Nanoscale." 2014, Presented at Seminar at Northwestern University,
  • "Integrating Biological and Engineering Transport at the Nanoscale." 2013, Presented at Seminar at Northwestern University,
  • "Fluorescent-Magnetic Nanomanipulators for Sensing and Separations." 2012, Presented at Sandia National Laboratories Center for Integrated Nanotechnologies User Conference,
  • "Multifunctional Nanocomposites for Single Cell and Molecule Manipulation." 2011, Presented at AIChE National Meeting,
  • "Magnetic Quantum Dots with Magnetic Microarrays for Molecular Detection and Separation." 2011, Presented at AIChE Annual Meeting,
  • "Nanoparticle-Based PCR-Less Detection and Isolation of Biomarkers." 2012, Presented at AIChE Annual Meeting,
  • "Separating Magnetically Labeled and Unlabeled Biological Cells within Microfluidic Channels Using Magnetic Nanodisks." 2012, Presented at AIChE Annual Meeting,
  • "Carbon-Iron Oxide Fluorescent-Magnetic Nanocomposites for In Vivo Imaging." 2011, Presented at AIChE Annual Meeting,
  • "Toxicity of Non-Cd-Based Fluorescent Nanoparticles for Biomedical Imaging." 2012, Presented at AIChE Annual Meeting,
  • "Magnetic Quantum Dots for Imaging, Diagnostics, and Biomechanical Manipulation." 2014, Presented at Seminar at University of Texas, Austin,
  • "Tunable, Aligned Electrospun Nanofiber White Matter Mimetics for Investigating Tumor Cell Migration." 2012, Presented at AIChE Annual Meeting,
  • "Towards an Engineered Nanofactory." 2013, Presented at Seminar at Sandia National Laboratories,
  • "Engineering a Bio-Inspired Nanofactory for Assembly, Capture and Transport." 2013, Presented at Seminar at Department of Chemical Engineering, Auburn University,
  • "Nanomaterials in Bioengineering: Tissue Engineering, Drug Delivery, and Imaging." 2014, Presented at Heaven and Earth Distinguished Lecture at Nanjing University,
  • "Synthesis and Manipulation of Multifunctional, Fluorescent-Magnetic Nanoparticles for Single Molecule Tracking." 2010, Presented at SPIE Photonics West,
  • "Nanotechnology for Neural Engineering." 2012, Presented at Department of Biomedical Engineering, Texas A&M University,
  • "Quantum Dots and Magnetic Quantum Dots for Biomedical Imaging and Separations." 2012, Presented at Seminar at Case Western Reserve University,
  • "Continuous Nanomanufacturing from Bench to Commercialization." 2013, Presented at Nano and Micro Manufacturing Workshop,
  • "Becoming a Woman Inventor and Entrepreneur." 2012, Presented at Professional Women's Resource Conference,
  • "Facile and Robust Fabrication of Sub-100 nm Poly(lactic-co-glycolic) acid Nanoparticle-based Drug Delivery Vehicles Via Self-Assembly." 2011, Presented at AIChE Annual Meeting,
  • "Magnetic Quantum Dots and Magnetic Microarrays for Cell and Molecular Detection." 2012, Presented at 6th Annual International Conference on Bioengineering and Nanotechnology,
  • "High Throughput Scalable Nanomanufacturing of Nanocomposites via Micellar Electrospray." 2014, Presented at 11th Korea-US Forum On Nanotechnology,
  • "Nanoengineered Platform for Molecular Capture, Detection, and Manipulation." 2013, Presented at 4th International Conference on Bioengineering,
  • "Surface-Functionalized Quantum Dots for Nerve Cell Binding and Stimulation." 2003, Presented at AIChE National Meeting,
  • "Fluorescent Magnetic Nanoparticles for Cell Manipulation and Imaging." 2009, Presented at 3rd Annual Symposium on Integrating Nanotechnology with Cell Biology and Neuroscience,
  • "Cell-Nanoparticle Interfaces Mediated by Biomolecular Recognition Molecules." 2002, Presented at AIChE National Meeting,
  • "Micro and Nanoscale Neural Prostheses." 2006, Presented at Department Seminar: OSU,
  • "Drug Delivery and Neural Prostheses." 2007, Presented at Department Seminar: OSU,
  • "Biological Response to Central Nervous System Implants." 2007, Presented at Biological Response to Central Nervous System Implants,
  • "A New Platform for Single Molecule Studies: Quantum Dot-Magnetic Nanoparticle Composites Coupled with Magnetic Tweezers." 2009, Presented at MRS Fall Meeting,
  • "Electrospun Fiber-Hydrogel Controlled Release Composites." 2010, Presented at BMES Annual Meeting,
  • "Alternating-Color Nanoparticles for Particle Tracking (Poster)." 2010, Presented at BMES Annual Meeting,
  • "Effect of Hydrophobicity on release of Hydrophilic Therapeutics from Hydrogel-Electrospun Fiber mat Composites Coatings." 2011, Presented at Society for Biomaterials Annual Meeting,

Papers in Proceedings

2014

  • Mahajan, K.D.; Vieira, G.; Ruan, G.; Bouxsein, N. et al. "Towards a biologically inspired nano-factory for molecular assembly, capture, transport, and characterization." (1 2014).
  • Q. Fan, G. Nabar, C. Miller, C. Castro, J. Winter "Photo-switchable quantum dots based on reversible FRET." in Proceedings of SPIE: Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XI. (7 2014).

2010

  • Ruan, G.; Thakur, D.; Hawkins, S.; Winter, J.O. "Synthesis and manipulation of multifunctional, fluorescent-magnetic nanoparticles for single molecule tracking." (1 2010).
  • Ruan, G.; Thakur, D.; Hawkins, S.; Winter, J.O. "Synthesis and manipulation of multifunctional, fluorescent-magnetic nanoparticles for single molecule tracking." (5 2010).
  • Ruan, G.; Thakur, D.; Hawkins, S.; Winter, J.O. "Synthesis and manipulation of multifunctional, fluorescent-magnetic nanoparticles for single molecule tracking." in Conference on Colloidal Quantum Dots for Biomedical Applications V. (1 2010).
  • G. Ruan, D. Thakur, S. Hawkins, J.O. Winter "Synthesis and manipulation of multifunctional, fluorescent-magnetic nanoparticles for single molecule tracking." in Proceedings of SPIE: Colloidal Quantum Dots for Biomedical Applications V.. (1 2010).
  • Ruan, G.; Thakur, D.; Deng, S.; Hawkins, S. et al. "Fluorescent-magnetic nanoparticles for imaging and cell manipulation." (1 2010).

2009

  • Winter, J.O.; Han, N.; Jensen, R.; Cogan, S.F. et al. "Adhesion molecules promote chronic neural interfaces following neurotrophin withdrawal." (12 2009).
  • Winter, J.O.; Han, N.; Jensen, R.; Cogan, S.F. et al. "Adhesion molecules promote chronic neural interfaces following neurotrophin withdrawal.." (12 2009).
  • Winter, J.O.; Han, N.; Jensen, R.; Cogan, S.F. et al. "Adhesion Molecules Promote Chronic Neural Interfaces Following Neurotrophin Withdrawal." (1 2009).
  • Winter, J.O.; Han, N.; Jensen, R.; Cogan, S.F. et al. "Adhesion Molecules Promote Chronic Neural Interfaces Following Neurotrophin Withdrawal." in Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society. (1 2009).
  • Winter, J.O.; Han, N.; Jensen, R.; Cogan, S.F. et al. "Adhesion molecules promote chronic neural interfaces following neurotrophin withdrawal.." (1 2009).
  • Winter, J.O.; Han, N.; Jensen, R.; Cogan, S.F. et al. "Adhesion molecules promote chronic neural interfaces following neurotrophin withdrawal.." (1 2009).
  • J.O. Winter, N. Han, R. Jensen, S.F. Cogan, J.F. Rizzo, III "Adhesion Molecules Promote Chronic Neural Interfaces Following Neurotrophin Withdrawal." in Proceedings of EMBS Annual Meeting. (1 2009).

2008

  • J.O. Winter, N. Han, M. Owens, J. Larison, J. Wheasler, K. Parikh, L. Siers "Polymer Hydrogel Thin Film Coatings for Acute Drug Delivery from Neural Prostheses." in PMSE Preprints. (1 2008).
  • Ruan, G.; Deng, S.; Thakur, D.; Han, N. et al. "Hybrid nanomaterials for molecular imaging and cellular engineering." (12 2008).

2005

  • Winter, J.O.; Gomez, N.; Korgel, B.A.; Schmidt, C.E. "Quantum dots for electrical stimulation of neural cells." in Conference on Nanobiophotonics and Biomedical Applications II. (1 2005).
  • J.O. Winter, N. Gomez, B.A. Korgel, C.E. Schmidt "Quantum Dots for Electrical Stimulation of Neural Cells." in Proceedings of SPIE: Nanobiophotonics and Biomedical Applications II. (1 2005).
  • Winter, J.O.; Gomez, N.; Korgel, B.A.; Schmidt, C.E. "Quantum dots for electrical stimulation of neural cells." (1 2005).
  • Winter, J.O.; Gomez, N.; Korgel, B.A.; Schmidt, C.E. "Quantum dots for electrical stimulation of neural cells." (8 2005).

2004

  • J.O. Winter, C.E. Schmidt, B.A. Korgel "Optimization of Quantum Dot-Nerve Cell Interfaces." in Quantum Dots: Nanoparticles and Nanowires, Proceedings of the 2003 Fall MRS Meeting.. (1 2004).

2002

  • J.O. Winter, C.E. Flynn, T.S. Liu, A.M. Belcher, B.A. Korgel, C.E. Schmidt "Semiconductor-Neural Interfaces." in Proceedings of the 2nd Annual Joint EMBS/BMES Conference. (1 2002).
  • Winter, J.O.; Flynn, C.E.; Liu, T.S.; Belcher, A.M. et al. "Semiconductor-neural interfaces." (1 2002).
  • Winter, J.O.; Flynn, C.E.; Liu, T.S.; Belcher, A.M. et al. "Semiconductor-neural interfaces." (12 2002).
  • Winter, J.O.; Flynn, C.E.; Liu, T.S.; Belcher, A.M. et al. "Semiconductor-neural interfaces." in 24th Annual International Conference of the Engineering-in-Medicine-and-Biology-Society/Annual Fall Meeting of the Biomedical-Engineering-Society (EMBS 2002 BMES). (1 2002).

Unknown

  • M.L. Howdyshell, M. Prikockis, S. Lauback, G.B. Vieira, K. Mahajan,J. Winter, R. Sooryakumar "Deterministic and stochastic trajectories of magnetic particles: Mapping energy landscapes for technology and biology." in IEEE Transactions on Magnetics.
  • "Fluorescent-Magnetic Nanoparticles for Imaging and Cell Manipulation." in Nanotechnology and Nanoengineering.
  • "Towards a Biologically Inspired Nano-factory for Molecular Assembly, Capture, Transport, and Characterization." in AIChE Annual Meeting.
  • "Synthesis and Manipulation of Multifunctional, Fluorescent-Magnetic Nanoparticles for Single Molecule Tracking." in SPIE Photonics West.
  • "Hybrid Nanomaterials for Molecular Imaging and Cellular Engineering." in AIChE National Meeting.