CBE Seminar: Hong-Cai Joe Zhou

Robert A. Welch Chair in Chemistry, Department of Chemistry, Texas A&M University

130 CBEC
130 CBEC
151 W Woodruff Ave
Columbus, OH 43210
United States

From Molecular to Mesoscopic Level: Pore Engineering and Its Catalytic Applications

The primary goal of pore engineering is the development of porous materials. It includes but is not limited to the generation of various levels (microporous, mesoporous, and macroporous) of porosity, the creation of hierarchically porous structures, pore surface modification, pore combination and partition, as well as the construction of composite materials.1 The presentation will start from molecular assembly of highly connected MOFs from basic building blocks.2 By tuning linker conformations and symmetries, we are able to discover a series of unprecedented topologies through systematic steric tuning, which can further serve as a blueprint for the design and construction of highly complicated porous structures. Subsequently, multiple ways of stable-MOF construction will be illustrated. The assembly of a synthetic toolkit, including linker labilization, linker thermolysis, linker reinstallation, and retrosynthetic analysis, enables the sophisticated design of a MOF target.3-5 Finally, we will illustrate a set of novel synthetic strategies to add structural complexity and functionality to an existing MOF by mesoscopic construction of multicomponent hierarchical MOFs.6-9 The utility of these pore engineering tools will be demonstrated through examples in heterogeneous catalysis.10-11


Kirchon, A.; Feng, L.; Drake, H. F.; Joseph, E. A.; Zhou, H.-C., Chem. Soc. Rev. 2018, 47, 8611-8638.
Wang, Y.; Feng, L.; Fan, W.; Wang, K.; Wang, X.; Wang, X.; Zhang, K.; Zhang, X.; Dai, F.; Sun, D.; Zhou, H.-C., J. Am. Chem. Soc. 2019, 141, 17, 6967-6975.
Yuan, S.; Zou, L.; Qin, J.-S.; Li, J.; Feng, L; Wang, X.; Bosch, M.; Alsalme, A.; Cagin, T.; Zhou, H.-C. Nat. Commun. 2017, 8, 15356.
Feng, L.; Yuan, S.; Zhang, L.-L.; Tan, K.; Li, J.-L.; Kirchon, A.; Liu, L.-M., Zhang, P.; Han, Y.; Chabal, Y. J.; Zhou, H.-C., J. Am. Chem. Soc. 2018, 140 (6), 2363-2372.
Feng, L.; Yuan, S.; Qin, J.-S.; Wang, Y.; Kirchon, A.; Qiu, D.; Cheng, L.; Madrahimov, S.; Zhou, H.-C., Matter, 2019, 1, 156-167.
Feng, L.; Yuan, S.; Li, J.-L.; Wang, K.-Y.; Gregory, D.; Zhang, P.; Wang, Y.; Zhou, H.-C., ACS Cent. Sci. 2018, 4, 12, 1719-1726.
Feng, L.; Li, J.; Gregory, D.; Lv, X.-L; Zhou, H.-C., Chem, 2019, 5, 1265–1274.
Feng, L.; Wang, K.-Y.; Gregory, D.; Zhou, H.-C., Chem. Soc. Rev. 2019, DOI: 10.1039/c9cs00250b.
Feng, L.; Lv, X.-L; Yan, T.-H.; Zhou, H.-C., J. Am. Chem. Soc. 2019, 141 (26), 10342-10349.
Wang, Y. ; Feng, L.; Pang, J.; Li, J.; Huang, N.; Day, G. S.; Cheng, L.; Drake, H. F.; Wang, Y.; Lollar, C.; Qin, J.; Gu, Z.; Lu, T.; Yuan, S.; Zhou, H.-C., Adv. Sci., 2019, 6, 1802059.
Feng, L. ; Wang, Y. ; Yuan, S.; Wang, K.; Li, J.; Day, G. S.; Qiu, D.; Cheng, L.; Chen, W.; Madrahimov, S.; Zhou, H.-C., ACS Catal. 2019, 9 (6), 5111-5118.


1989 Beijing Normal University, Beijing, China, BS and MS 
2000 Texas A&M University, College Station, PhD (Advisor: F. A. Cotton)

Rational synthesis and application of advanced porous materials including Metal-Organic Frameworks (MOFs), Porous Polymer Networks (PPNs), and Covalent and Coordination Cages:

1) Synthesis: synthesis of new MOFs with high stability, multiple components and hierarchical structures, developing new synthetic strategies for pore engineering;

2) Applications: catalysis, separation, storage, and biomedicine.



  • Highly Cited Researchers by Thomson Reuters (2014-2018)
  • The Association of Former Students Distinguished Research Achievement Award, Texas A&M University (2017)
  • Fellow, American Association for the Advancement of Science (2016)
  • Fellow, Royal Society of Chemistry (2016)
  • Fellow, American Chemical Society (2016)
  • Air Products Faculty Excellence Award (2007)
  • Miami University Distinguished Scholar Award (2006)
  • NSF CAREER Award (2005-2009); Cottrell Scholar Award (2005)
  • Research Innovation Award (2003)




Category: Seminar